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Cellosaurus Calu3-GemR (CVCL_EQ19)

[Text version]
Cell line name Calu3-GemR
Accession CVCL_EQ19
Resource Identification Initiative To cite this cell line use: Calu3-GemR (RRID:CVCL_EQ19)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:175901; Gemcitabine (Gemzar).
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Met237Ile (c.711G>T); ClinVar=VCV000634770; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0609 (Calu-3)
Sex of cell Male
Age at sampling 25Y
Category Cancer cell line
Publications

PubMed=17483357; DOI=10.1158/0008-5472.CAN-06-4495
Tooker P., Yen W.-C., Ng S.-C., Negro-Vilar A., Hermann T.W.
Bexarotene (LGD1069, Targretin), a selective retinoid X receptor agonist, prevents and reverses gemcitabine resistance in NSCLC cells by modulating gene amplification.
Cancer Res. 67:4425-4433(2007)

Cross-references
Cell line databases/resources cancercelllines; CVCL_EQ19
Encyclopedic resources Wikidata; Q54808428
Gene expression databases GEO; GSM159359
GEO; GSM159360
GEO; GSM159361
GEO; GSM159362
GEO; GSM159363
GEO; GSM159364
GEO; GSM159365
GEO; GSM159366
GEO; GSM159367
GEO; GSM159368
GEO; GSM159369
GEO; GSM159370
GEO; GSM159371
GEO; GSM159372
GEO; GSM159373
GEO; GSM159374
Entry history
Entry creation26-Sep-2016
Last entry update05-Oct-2023
Version number9