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Cellosaurus MCF7/XBP1 (CVCL_EQ29)

[Text version]
Cell line name MCF7/XBP1
Accession CVCL_EQ29
Resource Identification Initiative To cite this cell line use: MCF7/XBP1 (RRID:CVCL_EQ29)
Comments Population: Caucasian.
Transfected with: HGNC; 12801; XBP1.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=17660348; DOI=10.1096/fj.06-7990com
Gomez B.P., Riggins R.B., Shajahan A.N., Klimach U., Wang A.-F., Crawford A.C., Zhu Y.-L., Zwart A., Wang M.-Y., Clarke R.
Human X-box binding protein-1 confers both estrogen independence and antiestrogen resistance in breast cancer cell lines.
FASEB J. 21:4013-4027(2007)

Cross-references
Cell line databases/resources cancercelllines; CVCL_EQ29
Encyclopedic resources Wikidata; Q54904473
Gene expression databases GEO; GSM212608
GEO; GSM212609
GEO; GSM212610
Entry history
Entry creation26-Sep-2016
Last entry update05-Oct-2023
Version number13