Cellosaurus IGROV-1/Pt0.5 (CVCL_EQ61)

Cell line name IGROV-1/Pt0.5
Synonyms IGROV1/Pt0.5
Accession CVCL_EQ61
Resource Identification Initiative To cite this cell line use: IGROV-1/Pt0.5 (RRID:CVCL_EQ61)
Comments Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Sequence variations Heterozygous for BRCA1 p.Lys654fs*47 (from parent cell line).
Heterozygous for SMAD4 p.Gly231fs*10 (from parent cell line).
Heterozygous for PTEN p.Thr319fs*1 (c.955_958delACTT) (from parent cell line).
Heterozygous for TP53 p.Tyr126Cys (from parent cell line).
Disease Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1304 (IGROV-1)
Sex of cell Female
Age at sampling 47Y
Category Cancer cell line

PubMed=9636834; DOI=10.1023/A:1008265012435
Perego P., Romanelli S., Carenini N., Magnani I., Leone R., Bonetti A., Paolicchi A., Zunino F.
Ovarian cancer cisplatin-resistant cell lines: multiple changes including collateral sensitivity to taxol.
Ann. Oncol. 9:423-430(1998)