Home  |  Contact

Cellosaurus Hep-G2/PGC-1alpha 2x9 mutant (CVCL_EQ63)

[Text version]

Cell line name Hep-G2/PGC-1alpha 2x9 mutant
Accession CVCL_EQ63
Resource Identification Initiative To cite this cell line use: Hep-G2/PGC-1alpha 2x9 mutant (RRID:CVCL_EQ63)
Comments Transfected with: HGNC; 9237; PPARGC1A (with mutations in the 2nd and 3rd LXXLL motifs region).
Omics: Transcriptome analysis.
Sequence variations NRAS p.Gln61Leu (c.182A>T) (ClinVar=VCV000375874) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line

PubMed=17157261; DOI=10.1016/j.molcel.2006.10.012
Gaillard S., Grasfeder L.L., Haeffele C.L., Lobenhofer E.K., Chu T.-M., Wolfinger R., Kazmin D., Koves T.R., Muoio D.M., Chang C.-Y., McDonnell D.P.
Receptor-selective coactivators as tools to define the biology of specific receptor-coactivator pairs.
Mol. Cell 24:797-803(2006)

Gene expression databases GEO; GSM138622
GEO; GSM138623
GEO; GSM138624
Other Wikidata; Q54882790
Entry history
Entry creation26-Sep-2016
Last entry update02-Jul-2020
Version number7