ID   Hep-G2/PGC-1alpha L2L3 mutant
AC   CVCL_EQ64
DR   GEO; GSM138628
DR   GEO; GSM138629
DR   GEO; GSM138630
DR   Wikidata; Q54882791
RX   PubMed=17157261;
CC   Sequence variation: NRAS p.Gln61Leu (c.182A>T) (ClinVar=VCV000375874) (from parent cell line).
CC   Sequence variation: TERT c.228C>T (-124C>T); in promoter (from parent cell line).
CC   Transfected with: HGNC; 9237; PPARGC1A (with Leu to Ala mutations in the 2nd and 3rd LXXLL motifs).
CC   Omics: Transcriptome analysis.
DI   NCIt; C3728; Hepatoblastoma
DI   ORDO; Orphanet_449; Hepatoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0027 ! Hep-G2
SX   Male
AG   15Y
CA   Cancer cell line
DT   Created: 26-09-16; Last updated: 02-07-20; Version: 7
//
RX   PubMed=17157261; DOI=10.1016/j.molcel.2006.10.012;
RA   Gaillard S., Grasfeder L.L., Haeffele C.L., Lobenhofer E.K., Chu T.-M.,
RA   Wolfinger R., Kazmin D., Koves T.R., Muoio D.M., Chang C.-Y.,
RA   McDonnell D.P.;
RT   "Receptor-selective coactivators as tools to define the biology of
RT   specific receptor-coactivator pairs.";
RL   Mol. Cell 24:797-803(2006).
//