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Cellosaurus A431-PR (CVCL_EQ67)

[Text version]

Cell line name A431-PR
Synonyms A431 PR
Accession CVCL_EQ67
Resource Identification Initiative To cite this cell line use: A431-PR (RRID:CVCL_EQ67)
Comments Knockout cell: Method=shRNA knockdown; HGNC; 9588; PTEN.
Omics: Transcriptome analysis.
Sequence variations EGFR-PPARGC1A gene fusion (from parent cell line).
TP53 p.Arg273His (c.818G>A) (from parent cell line).
Disease Vulvar squamous cell carcinoma (NCIt: C4052)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0037 (A-431)
Sex of cell Female
Age at sampling 85Y
Category Cancer cell line

PubMed=17560336; DOI=10.1016/j.ccr.2007.04.021
Vivanco I., Palaskas N., Tran C., Finn S.P., Getz G., Kennedy N.J., Jiao J., Rose J., Xie W., Loda M., Golub T.R., Mellinghoff I.K., Davis R.J., Wu H., Sawyers C.L.
Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN.
Cancer Cell 11:555-569(2007)

Gene expression databases GEO; GSM183434
GEO; GSM183435
Other Wikidata; Q54606915
Entry history
Entry creation26-Sep-2016
Last entry updated24-May-2019
Version number4