Cellosaurus A431-PR (CVCL_EQ67)

Cell line name A431-PR
Synonyms A431 PR
Accession CVCL_EQ67
Resource Identification Initiative To cite this cell line use: A431-PR (RRID:CVCL_EQ67)
Comments Knockout cell: Method=shRNA knockdown; HGNC; 9588; PTEN.
Sequence variation: TP53 p.Arg273His (from parent cell line).
Omics: Transcriptome analysis.
Disease Vulvar squamous cell carcinoma (NCIt: C4052)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0037 (A-431)
Sex of cell Female
Age at sampling 85Y
Category Cancer cell line

PubMed=17560336; DOI=10.1016/j.ccr.2007.04.021
Vivanco I., Palaskas N., Tran C., Finn S.P., Getz G., Kennedy N.J., Jiao J., Rose J., Xie W., Loda M., Golub T.R., Mellinghoff I.K., Davis R.J., Wu H., Sawyers C.L.
Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN.
Cancer Cell 11:555-569(2007)

Gene expression databases GEO; GSM183434
GEO; GSM183435