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Cellosaurus HCC827-PR (CVCL_EQ68)

[Text version]

Cell line name HCC827-PR
Synonyms HCC827 PR
Accession CVCL_EQ68
Resource Identification Initiative To cite this cell line use: HCC827-PR (RRID:CVCL_EQ68)
Comments Knockout cell: Method=shRNA knockdown; HGNC; 9588; PTEN.
Omics: Transcriptome analysis.
Sequence variations Heterozygous for EGFR p.Glu746_Ala750del (c.2236_2250del15) (from parent cell line).
Homozygous for TP53 p.Val218del (c.652_654delGTG) (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2063 (HCC827)
Sex of cell Female
Age at sampling 39Y
Category Cancer cell line

PubMed=17560336; DOI=10.1016/j.ccr.2007.04.021
Vivanco I., Palaskas N., Tran C., Finn S.P., Getz G., Kennedy N.J., Jiao J., Rose J., Xie W., Loda M., Golub T.R., Mellinghoff I.K., Davis R.J., Wu H., Sawyers C.L.
Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN.
Cancer Cell 11:555-569(2007)

Gene expression databases GEO; GSM183438
GEO; GSM183439
Other Wikidata; Q54881804
Entry history
Entry creation26-Sep-2016
Last entry update12-Mar-2020
Version number5