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Cellosaurus SKBR3-PR (CVCL_EQ69)

[Text version]
Cell line name SKBR3-PR
Synonyms SKBR3 PR
Accession CVCL_EQ69
Resource Identification Initiative To cite this cell line use: SKBR3-PR (RRID:CVCL_EQ69)
Comments Population: Caucasian.
Knockout cell: Method=shRNA knockdown; HGNC; 9588; PTEN.
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; 1748; CDH1; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0033 (SK-BR-3)
Sex of cell Female
Age at sampling 43Y
Category Cancer cell line
Publications

PubMed=17560336; DOI=10.1016/j.ccr.2007.04.021
Vivanco I., Palaskas N., Tran C., Finn S.P., Getz G., Kennedy N.J., Jiao J., Rose J., Xie W.-L., Loda M., Golub T.R., Mellinghoff I.K., Davis R.J., Wu H., Sawyers C.L.
Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN.
Cancer Cell 11:555-569(2007)

Cross-references
Cell line databases/resources cancercelllines; CVCL_EQ69
Encyclopedic resources Wikidata; Q54954676
Gene expression databases GEO; GSM183442
GEO; GSM183443
Entry history
Entry creation26-Sep-2016
Last entry update05-Oct-2023
Version number10