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Cellosaurus SKBR3-PR (CVCL_EQ69)

[Text version]

Cell line name SKBR3-PR
Synonyms SKBR3 PR
Accession CVCL_EQ69
Resource Identification Initiative To cite this cell line use: SKBR3-PR (RRID:CVCL_EQ69)
Comments Knockout cell: Method=shRNA knockdown; HGNC; 9588; PTEN.
Omics: Transcriptome analysis.
Sequence variations Homozygous for CDH1 deletion (from parent cell line).
Homozygous for TP53 p.Arg175His (c.524G>A) (ClinVar=VCV000012374) (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0033 (SK-BR-3)
Sex of cell Female
Age at sampling 43Y
Category Cancer cell line
Publications

PubMed=17560336; DOI=10.1016/j.ccr.2007.04.021
Vivanco I., Palaskas N., Tran C., Finn S.P., Getz G., Kennedy N.J., Jiao J., Rose J., Xie W., Loda M., Golub T.R., Mellinghoff I.K., Davis R.J., Wu H., Sawyers C.L.
Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN.
Cancer Cell 11:555-569(2007)

Cross-references
Gene expression databases GEO; GSM183442
GEO; GSM183443
Other Wikidata; Q54954676
Entry history
Entry creation26-Sep-2016
Last entry update02-Jul-2020
Version number5