ID   SKBR3-PR
AC   CVCL_EQ69
SY   SKBR3 PR
DR   cancercelllines; CVCL_EQ69
DR   GEO; GSM183442
DR   GEO; GSM183443
DR   Wikidata; Q54954676
RX   PubMed=17560336;
CC   Population: Caucasian.
CC   Knockout cell: Method=shRNA knockdown; HGNC; 9588; PTEN.
CC   Sequence variation: Gene deletion; HGNC; 1748; CDH1; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (from parent cell line).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C5214; Breast adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0033 ! SK-BR-3
SX   Female
AG   43Y
CA   Cancer cell line
DT   Created: 26-09-16; Last updated: 05-10-23; Version: 10
//
RX   PubMed=17560336; DOI=10.1016/j.ccr.2007.04.021;
RA   Vivanco I., Palaskas N., Tran C., Finn S.P., Getz G., Kennedy N.J.,
RA   Jiao J., Rose J., Xie W.-L., Loda M., Golub T.R., Mellinghoff I.K.,
RA   Davis R.J., Wu H., Sawyers C.L.;
RT   "Identification of the JNK signaling pathway as a functional target of
RT   the tumor suppressor PTEN.";
RL   Cancer Cell 11:555-569(2007).
//