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Cellosaurus ND27760 (CVCL_F204)

[Text version]
Cell line name ND27760
Accession CVCL_F204
Resource Identification Initiative To cite this cell line use: ND27760 (RRID:CVCL_F204)
Comments Population: Caucasian.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Gene amplification; HGNC; 11138; SNCA; Triplication; Zygosity=Heterozygous (PubMed=22952635).
Disease Parkinson disease 4, autosomal dominant (NCIt: C198604)
Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_DD64 (A23-iPSC)CVCL_DD59 (A6-iPSC)CVCL_AW97 (EDi001-A)
CVCL_ZA47 (EDi001-B)CVCL_A8ME (LCSBi007-A)CVCL_A8MF (LCSBi007-B)
CVCL_F202 (ND34391)CVCL_RN26 (ND50040)CVCL_RN27 (ND50041)
CVCL_RN28 (ND50042)CVCL_T869 (PARK4-14)CVCL_T870 (PARK4-4)
Originate from same individual CVCL_L024 ! GM15844
CVCL_F203 ! ND00139
Sex of cell Female
Age at sampling 55Y
Category Finite cell line
STR profile Source(s): PubMed=27191603

Markers:
AmelogeninX
CSF1PO12
D5S81811
D7S8209,11
D13S3179,11
D16S53911,12
D21S1130,31.2
TH017,9.3
TPOX8,11
vWA15,18

Run an STR similarity search on this cell line
Publications

PubMed=22952635; DOI=10.1371/journal.pone.0043099
Wray S., Self M., Lewis P.A., Taanman J.-W., Ryan N.S., Mahoney C.J., Liang Y.-Y., Devine M.J., Sheerin U.-M., Houlden H., Morris H.R., Healy D., Marti-Masso J.-F., Preza E., Barker S., Sutherland M., Corriveau R.A., D'Andrea M., Schapira A.H.V., Uitti R.J., Guttman M., Opala G., Jasinska-Myga B., Puschmann A., Nilsson C., Espay A.J., Slawek J., Gutmann L., Boeve B.F., Boylan K., Stoessl A.J., Ross O.A., Maragakis N.J., Van Gerpen J.A., Gerstenhaber M., Gwinn-Hardy K.A., Dawson T.M., Isacson O., Marder K.S., Clark L.N., Przedborski S.E., Finkbeiner S., Rothstein J.D., Wszolek Z.K., Rossor M.N., Hardy J.
Creation of an open-access, mutation-defined fibroblast resource for neurological disease research.
PLoS ONE 7:E43099-E43099(2012)

PubMed=27191603; DOI=10.1371/journal.pone.0154890
Momcilovic O., Sivapatham R., Oron T.R., Meyer M., Mooney S., Rao M.S., Zeng X.-M.
Derivation, characterization, and neural differentiation of integration-free induced pluripotent stem cell lines from Parkinson's disease patients carrying SNCA, LRRK2, PARK2, and GBA mutations.
PLoS ONE 11:E0154890-E0154890(2016)

PubMed=34826737; DOI=10.1016/j.scr.2021.102600
Novak G., Finkbeiner S., Skibinski G., Skupin A.
Generation of two human induced pluripotent stem cell lines (iPSCs) with mutations of the alpha-synuclein (SNCA) gene associated with Parkinson's disease; the A53T mutation (LCSBi003) and a triplication of the SNCA gene (LCSBi007).
Stem Cell Res. 57:102600-102600(2021)

Cross-references
Cell line collections (Providers) Coriell; ND27760 - Discontinued
NHCDR; ND27760
Encyclopedic resources Wikidata; Q54929071
Entry history
Entry creation22-Oct-2012
Last entry update29-Jun-2023
Version number20