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Cellosaurus XP2OS (CVCL_F510)

[Text version]

Cell line name XP2OS
Synonyms Xeroderma Pigmentosum 2 OSaka
Accession CVCL_F510
Resource Identification Initiative To cite this cell line use: XP2OS (RRID:CVCL_F510)
Comments Population: Japanese.
Misspelling: XP20S; Occasionally.
Derived from sampling site: Skin.
Sequence variations Homozygous for XPA c.390-1G>C (IVS3-1G>C) (ClinVar=VCV000264684); Note=Splice acceptor mutation (PubMed=1702221).
Disease Xeroderma pigmentosum, complementation group A (NCIt: C3965)
Xeroderma pigmentosum (ORDO: Orphanet_910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_ZN80 (XP2OS SV40-transformed)CVCL_3242 (XP2OS(SV))
Originate from same individual CVCL_F512 ! XP2OS LCL
Sex of cell Female
Age at sampling 7Y
Category Finite cell line
STR profile Source(s): JCRB


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PubMed=1180926; DOI=10.1016/0006-291x(75)90551-3
Fujiwara Y., Tatsumi M.
Repair of mitomycin C damage to DNA in mammalian cells and its impairment in Fanconi's anemia cells.
Biochem. Biophys. Res. Commun. 66:592-598(1975)

PubMed=967189; DOI=10.1016/0027-5107(76)90058-0
Fujiwara Y., Tatsumi M.
Replicative bypass repair of ultraviolet damage to DNA of mammalian cells: caffeine sensitive and caffeine resistant mechanisms.
Mutat. Res. 37:91-110(1976)

Takebe H., Miki Y., Kozuka T., Furuyama J.-I., Tanaka K.
DNA repair characteristics and skin cancers of xeroderma pigmentosum patients in Japan.
Cancer Res. 37:490-495(1977)

PubMed=7000335; DOI=10.1016/0304-3835(80)90072-5
Ishizaki K., Yagi T., Takebe H.
Cytotoxic effects of protease inhibitors on human cells. 1. High sensitivity of xeroderma pigmentosum cells to antipain.
Cancer Lett. 10:199-205(1980)

PubMed=7264357; DOI=10.1111/1523-1747.ep12482447
Fujiwara Y., Ichihashi M., Kano Y., Goto K., Shimizu K.
A new human photosensitive subject with a defect in the recovery of DNA synthesis after ultraviolet-light irradiation.
J. Invest. Dermatol. 77:256-263(1981)

PubMed=6876478; DOI=10.1007/BF01897042
Ikenaga M., Midorikawa M., Abe J., Mimaki T.
The sensitivities to radiations and radiomimetic chemicals of cells from patients with ataxia telangiectasia.
Jinrui Idengaku Zasshi 28:1-10(1983)

PubMed=1702221; DOI=10.1073/pnas.87.24.9908
Satokata I., Tanaka K., Miura N., Miyamoto I., Satoh Y., Kondo S., Okada Y.
Characterization of a splicing mutation in group A xeroderma pigmentosum.
Proc. Natl. Acad. Sci. U.S.A. 87:9908-9912(1990)

Yagi T., Tatsumi-Miyajima J., Sato M., Kraemer K.H., Takebe H.
Analysis of point mutations in an ultraviolet-irradiated shuttle vector plasmid propagated in cells from Japanese xeroderma pigmentosum patients in complementation groups A and F.
Cancer Res. 51:3177-3182(1991)

PubMed=1372102; DOI=10.1016/0921-8777(92)90080-M
Satokata I., Tanaka K., Miura N., Narita M., Mimaki T., Satoh Y., Kondo S., Okada Y.
Three nonsense mutations responsible for group A xeroderma pigmentosum.
Mutat. Res. 273:193-202(1992)

Cell line collections JCRB; JCRB3048
JCRB; KURB1007 - Discontinued
Other Wikidata; Q54838478
Entry history
Entry creation11-Feb-2013
Last entry update12-Jan-2021
Version number18