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Cellosaurus AT22IJE-T pEBS7 (CVCL_F635)

[Text version]
Cell line name AT22IJE-T pEBS7
Synonyms GM16666; pEBS
Accession CVCL_F635
Resource Identification Initiative To cite this cell line use: AT22IJE-T pEBS7 (RRID:CVCL_F635)
Comments Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; 795; ATM; Simple; p.Leu762Valfs*2 (c.2282_2283CT[1]) (c.2284_2285delCT); ClinVar=VCV000141325; Zygosity=Unspecified (from parent cell line).
Disease Ataxia telangiectasia syndrome (NCIt: C2887)
Ataxia telangiectasia (ORDO: Orphanet_100)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D566 (AT22IJE-T)
Sex of cell Female
Age at sampling 5Y
Category Transformed cell line
Publications

PubMed=9244351; DOI=10.1038/sj.onc.1201319
Ziv Y., Bar-Shira A., Pecker I., Russell P., Jorgensen T.J., Tsarfati I., Shiloh Y.
Recombinant ATM protein complements the cellular A-T phenotype.
Oncogene 15:159-167(1997)

PubMed=19962312; DOI=10.1016/j.cub.2009.10.040
Hamilton G., Yee K.S., Scrace S., O'Neill E.
ATM regulates a RASSF1A-dependent DNA damage response.
Curr. Biol. 19:2020-2025(2009)

Cross-references
Cell line collections (Providers) Coriell; GM16666
Cell line databases/resources CLO; CLO_0017459
Encyclopedic resources Wikidata; Q54848692
Entry history
Entry creation11-Feb-2013
Last entry update29-Jun-2023
Version number13