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Cellosaurus KS Y-1 (CVCL_F660)

Cell line name KS Y-1
Synonyms KS Y1; KSY-1
Accession CVCL_F660
Resource Identification Initiative To cite this cell line use: KS Y-1 (RRID:CVCL_F660)
Comments Problematic cell line: Contaminated. Shown to be a T24 derivative (PubMed=22987579). Was thought to originate from the pleural effusion of a male AIDS patient with Kaposi sarcoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00408.
Sequence variations Homozygous for HRAS p.Gly12Val (c.35G>T) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0554 (T24)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
Web pages https://www.atcc.org/support/faqs/93f92/KSY1%20ATCC%20CRL11448-1061.aspx

PubMed=7629884; DOI=10.1093/jnci/87.13.974
Lunardi-Iskandar Y., Gill P., Lam V.H., Zeman R.A., Michaels F., Mann D.L., Reitz M.S. Jr., Kaplan M., Berneman Z.N., Carter D., Bryant J.L., Gallo R.C.
Isolation and characterization of an immortal neoplastic cell line (KS Y-1) from AIDS-associated Kaposi's sarcoma.
J. Natl. Cancer Inst. 87:974-981(1995)

Lunardi-Iskandar Y., Gallo R.C.
First immortalized Kaposi's sarcoma cell line.
Patent number US5569602, 29-Oct-1996

Boshoff C.
Kaposi's sarcoma.
(In) Human cell culture. Vol. 2. Cancer Cell Lines part 2; Masters J.R.W., Palsson B.O. (eds.); pp.157-166; Kluwer Academic Publishers; New York (1999)

PubMed=22987579; DOI=10.1002/ijc.27849
Sturzl M., Gaus D., Dirks W.G., Ganem D., Jochmann R.
Kaposi's sarcoma-derived cell line SLK is not of endothelial origin, but is a contaminant from a known renal carcinoma cell line.
Int. J. Cancer 132:1954-1958(2013)

Cell line collections ATCC; CRL-11448 - Discontinued
Biological sample resources BioSample; SAMN03151948
Other Wikidata; Q54900488