Home  |  Contact

Cellosaurus XMMCO-791 (CVCL_F815)

Cell line name XMMCO-791
Synonyms 791
Accession CVCL_F815
Resource Identification Initiative To cite this cell line use: XMMCO-791 (RRID:CVCL_F815)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); HB-9173.
Biotechnology: Was used to produce monoclonal antibody MoAb 791T which when conjugated to ricin chain A produces XomaZyme-791 (79IT/36-RTA). XomaZyme-791 was evaluated in two phase 1 clinical trials to treat patients with metastatic colorectal carcinoma (DOI=10.3390/antib1010039).
Monoclonal antibody isotype: IgG2b.
Monoclonal antibody target: Human colorectal tumour-associated antigen.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2155 (P3/NS1/1-Ag4.1)
Category Hybridoma
Publications

Patent=US4708862
Baldwin R.W.
Radioimmuno detection of human cancers using anti-tumor monoclonal antibody.
Patent number US4708862, 24-Nov-1987

Patent=US4925922
Byers V.S., Baldwin R.W., Scannon P.J.
Potentiation of cytotoxic conjugates.
Patent number US4925922, 15-May-1990

DOI=10.3390/antib1010039
Becker N., Benhar I.
Antibody-based immunotoxins for the treatment of cancer.
Antibodies 1:39-69(2012)

Cross-references
Cell line collections (Providers) ATCC; HB-9173
Cell line databases/resources CLO; CLO_0009650
Encyclopedic resources Wikidata; Q54994847
Entry history
Entry creation11-Feb-2013
Last entry update21-Mar-2023
Version number6