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Cellosaurus U-87MG Uppsala (CVCL_GP63)

[Text version]

Cell line name U-87MG Uppsala
Synonyms U-87MG; U-87 MG; U87 MG; U-87-MG; U87-MG; U87MG; U-87; U87; 87 MG; 87MG
Accession CVCL_GP63
Resource Identification Initiative To cite this cell line use: U-87MG Uppsala (RRID:CVCL_GP63)
Comments Caution: This is the original U-87MG cell line established in 1968 at the University of Uppsala. The cell line distributed by most cell collections (including ATCC, CLS, ECACC, etc.) is a different cell line whose origin is not yet clear (PubMed=27582061). See U-87MG ATCC (CVCL_0022) for the cell line used by most research groups.
Disease Glioblastoma (NCIt: C3058)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 44Y
Category Cancer cell line
STR profile Source(s): PubMed=27582061

Markers:
AmelogeninX
CSF1PO10,11
D2S133817,20
D3S135815
D5S81811,12
D7S82010,13
D8S117913,14
D13S31711,12
D16S5399,13
D19S43314,15
D21S1128,30
FGA20,24
Penta D11
Penta E7,13
TH018,9
TPOX8,11
vWA15,19

Run an STR similarity search on this cell line
Web pages https://en.wikipedia.org/wiki/U87
Publications

PubMed=4313504; DOI=10.1111/j.1699-0463.1968.tb03502.x
Ponten J., Macintyre E.H.
Long term culture of normal and neoplastic human glia.
Acta Pathol. Microbiol. Scand. 74:465-486(1968)

PubMed=4337530; DOI=10.1111/j.1699-0463.1972.tb02176.x
Macintyre E.H., Ponten J., Vatter A.E.
The ultrastructure of human and murine astrocytes and of human fibroblasts in culture.
Acta Pathol. Microbiol. Scand. A. 80:267-283(1972)

PubMed=4134536; DOI=10.1002/ijc.2910120215
Westermark B.
The deficient density-dependent growth control of human malignant glioma cells and virus-transformed glia-like cells in culture.
Int. J. Cancer 12:438-451(1973)

PubMed=4369403; DOI=10.1002/1097-0142(197408)34:2<274::AID-CNCR2820340209>3.0.CO;2-4
Wahlstrom T., Linder E., Saksela E., Westermark B.
Tumor-specific membrane antigens in established cell lines from gliomas.
Cancer 34:274-279(1974)

DOI=10.1007/978-1-4757-1647-4_7
Ponten J.
Neoplastic human glia cells in culture.
(In) Human tumor cells in vitro; Fogh J. (eds.); pp.175-206; Springer; New York (1975)

PubMed=2454731
Nister M., Libermann T.A., Betsholtz C., Pettersson M., Claesson-Welsh L., Heldin C.-H., Schlessinger J., Westermark B.
Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines.
Cancer Res. 48:3910-3918(1988)

DOI=10.1016/B978-0-12-333530-2.50005-8
Nister M., Westermark B.
Human glioma cell lines.
(In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.17-42; Academic Press; New York (1994)

PubMed=27582061; DOI=10.1126/scitranslmed.aaf6853
Allen M., Bjerke M., Edlund H., Nelander S., Westermark B.
Origin of the U87MG glioma cell line: good news and bad news.
Sci. Transl. Med. 8:354re3-354re3(2016)

Cross-references
Other Wikidata; Q28575999
Entry history
Entry creation26-Sep-2016
Last entry updated05-Mar-2018
Version number4