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Cellosaurus U-87MG Uppsala (CVCL_GP63)

Cell line name U-87MG Uppsala
Synonyms U-87MG; U-87 MG; U87 MG; U-87-MG; U87-MG; U87MG; U-87; U87; 87 MG; 87MG
Accession CVCL_GP63
Resource Identification Initiative To cite this cell line use: U-87MG Uppsala (RRID:CVCL_GP63)
Comments Caution: This is the original U-87MG cell line established in 1968 at the University of Uppsala. The cell line distributed by most cell collections (including ATCC, CLS, ECACC, etc.) is a different cell line whose origin is not yet clear (PubMed=27582061). See U-87MG ATCC (CVCL_0022) for the cell line used by most research groups.
Disease Glioblastoma (NCIt: C3058)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 44Y
Category Cancer cell line
STR profile Source(s): PubMed=27582061

Markers:
AmelogeninX
CSF1PO10,11
D13S31711,12
D16S5399,13
D19S43314,15
D21S1128,30
D2S133817,20
D3S135815
D5S81811,12
D7S82010,13
D8S117913,14
FGA20,24
Penta D11
Penta E7,13
TH018,9
TPOX8,11
vWA15,19
Web pages https://en.wikipedia.org/wiki/U87
Publications

PubMed=4313504; DOI=10.1111/j.1699-0463.1968.tb03502.x
Ponten J., Macintyre E.H.
Long term culture of normal and neoplastic human glia.
Acta Pathol. Microbiol. Scand. 74:465-486(1968)

PubMed=4337530; DOI=10.1111/j.1699-0463.1972.tb02176.x
Macintyre E.H., Ponten J., Vatter A.E.
The ultrastructure of human and murine astrocytes and of human fibroblasts in culture.
Acta Pathol. Microbiol. Scand. A. 80:267-283(1972)

PubMed=4134536; DOI=10.1002/ijc.2910120215
Westermark B.
The deficient density-dependent growth control of human malignant glioma cells and virus-transformed glia-like cells in culture.
Int. J. Cancer 12:438-451(1973)

PubMed=4369403; DOI=10.1002/1097-0142(197408)34:2<274::AID-CNCR2820340209>3.0.CO;2-4
Wahlstrom T., Linder E., Saksela E., Westermark B.
Tumor-specific membrane antigens in established cell lines from gliomas.
Cancer 34:274-279(1974)

DOI=10.1007/978-1-4757-1647-4_7
Ponten J.
Neoplastic human glia cells in culture.
(In) Human tumor cells in vitro; Fogh J. (eds.); pp.175-206; Springer; New York (1975)

PubMed=2454731
Nister M., Libermann T.A., Betsholtz C., Pettersson M., Claesson-Welsh L., Heldin C.-H., Schlessinger J., Westermark B.
Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines.
Cancer Res. 48:3910-3918(1988)

DOI=10.1016/B978-0-12-333530-2.50005-8
Nister M., Westermark B.
Human glioma cell lines.
(In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.17-42; Academic Press; New York (1994)

PubMed=27582061; DOI=10.1126/scitranslmed.aaf6853
Allen M., Bjerke M., Edlund H., Nelander S., Westermark B.
Origin of the U87MG glioma cell line: good news and bad news.
Sci. Transl. Med. 8:354re3-354re3(2016)

Cross-references
Other Wikidata; Q28575999