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Cellosaurus T47D:A18 (CVCL_GY01)

[Text version]

Cell line name T47D:A18
Synonyms A18
Accession CVCL_GY01
Resource Identification Initiative To cite this cell line use: T47D:A18 (RRID:CVCL_GY01)
Sequence variations Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Leu194Phe (c.580C>T); ClinVar=VCV000127817; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0553 (T-47D)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line

Murphy C.S., Pink J.J., Jordan V.C.
Characterization of a receptor-negative, hormone-nonresponsive clone derived from a T47D human breast cancer cell line kept under estrogen-free conditions.
Cancer Res. 50:7285-7292(1990)

PubMed=8883409; DOI=10.1038/bjc.1996.521
Pink J.J., Bilimoria M.M., Assikis J., Jordan V.C.
Irreversible loss of the oestrogen receptor in T47D breast cancer cells following prolonged oestrogen deprivation.
Br. J. Cancer 74:1227-1236(1996)

Other Wikidata; Q54971580
Entry history
Entry creation26-Sep-2016
Last entry update20-May-2021
Version number8