Cell line name |
T47D:C4 |
Accession |
CVCL_GY02 |
Resource Identification Initiative |
To cite this cell line use: T47D:C4 (RRID:CVCL_GY02) |
Comments |
Population: Caucasian. Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175. |
Sequence variations |
- Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Leu194Phe (c.580C>T); ClinVar=VCV000127817; Zygosity=Homozygous (from parent cell line).
|
Disease |
Invasive breast carcinoma of no special type (NCIt: C4194) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_0553 (T-47D) Children:
|
Sex of cell |
Female |
Age at sampling |
54Y |
Category |
Cancer cell line |
Publications | PubMed=2632259; DOI=10.1016/0277-5379(89)90348-9 Murphy C.S., Meisner L.F., Wu S.-Q., Jordan V.C. Short- and long-term estrogen deprivation of T47D human breast cancer cells in culture. Eur. J. Cancer Clin. Oncol. 25:1777-1788(1989) PubMed=2224859 Murphy C.S., Pink J.J., Jordan V.C. Characterization of a receptor-negative, hormone-nonresponsive clone derived from a T47D human breast cancer cell line kept under estrogen-free conditions. Cancer Res. 50:7285-7292(1990) PubMed=8883409; DOI=10.1038/bjc.1996.521 Pink J.J., Bilimoria M.M., Assikis V.J., Jordan V.C. Irreversible loss of the oestrogen receptor in T47D breast cancer cells following prolonged oestrogen deprivation. Br. J. Cancer 74:1227-1236(1996) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_GY02
|
Encyclopedic resources |
Wikidata; Q54971581
|
Entry history |
Entry creation | 26-Sep-2016 |
Last entry update | 05-Oct-2023 |
Version number | 11 |
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