ID   A431/CDDP1
AC   CVCL_GY97
DR   cancercelllines; CVCL_GY97
DR   Wikidata; Q54606917
RX   PubMed=9755302;
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
CC   Sequence variation: Gene fusion; HGNC; 3236; EGFR + HGNC; 9237; PPARGC1A; Name(s)=EGFR-PPARGC1A (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
CC   Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
DI   NCIt; C4819; Skin squamous cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0037 ! A-431
SX   Female
AG   85Y
CA   Cancer cell line
DT   Created: 26-09-16; Last updated: 05-10-23; Version: 12
//
RX   PubMed=9755302; DOI=10.1159/000007153;
RA   Mese H., Sasaki A., Alcalde R.E., Nakayama S., Matsumura T.;
RT   "Establishment and characterization of cisplatin-resistant human
RT   epidermoid carcinoma cell line, A431 cell.";
RL   Chemotherapy 44:414-420(1998).
//