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Cellosaurus BE [Human colon carcinoma] (CVCL_H580)

[Text version]
Cell line name BE [Human colon carcinoma]
Accession CVCL_H580
Resource Identification Initiative To cite this cell line use: BE [Human colon carcinoma] (RRID:CVCL_H580)
Comments Part of: KuDOS 95 cell line panel.
From: Giovanella B.C.; St. Joseph's Hospital Cancer Research Laboratory; Houston; USA.
Omics: Transcriptome analysis by microarray.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Gly464Val (c.1391G>T); ClinVar=VCV000040364; Zygosity=Unspecified (PubMed=12068308).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Unspecified (PubMed=12068308).
Disease Colon carcinoma (NCIt: C4910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_H581 (BE-NQ2)CVCL_H582 (BE-NQ3)CVCL_H583 (BE-NQ4)
CVCL_H584 (BE-NQ5)CVCL_H585 (BE-NQ7)
Sex of cell Male
Age at sampling 63Y
Category Cancer cell line
Publications

PubMed=626984
Erickson L.C., Osieka R., Kohn K.W.
Differential repair of 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1- nitrosourea-induced DNA damage in two human colon tumor cell lines.
Cancer Res. 38:802-808(1978)

PubMed=6256643; DOI=10.1038/288724a0
Day R.S. III, Ziolkowski C.H.J., Scudiero D.A., Meyer S.A., Lubiniecki A.S., Girardi A.J., Galloway S.M., Bynum G.D.
Defective repair of alkylated DNA by human tumour and SV40-transformed human cell strains.
Nature 288:724-727(1980)

PubMed=22282976; DOI=10.1093/carcin/1.1.21
Day R.S. III, Ziolkowski C.H.J., Scudiero D.A., Meyer S.A., Mattern M.R.
Human tumor cell strains defective in the repair of alkylation damage.
Carcinogenesis 1:21-32(1980)

PubMed=1737339
Traver R.D., Horikoshi T., Danenberg K.D., Stadlbauer T.H.W., Danenberg P.V., Ross D., Gibson N.W.
NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity.
Cancer Res. 52:797-802(1992)

PubMed=9865924
Winski S.L., Hargreaves R.H.J., Butler J., Ross D.
A new screening system for NAD(P)H:quinone oxidoreductase (NQO1)-directed antitumor quinones: identification of a new aziridinylbenzoquinone, RH1, as a NQO1-directed antitumor agent.
Clin. Cancer Res. 4:3083-3088(1998)

PubMed=12068308; DOI=10.1038/nature00766
Davies H., Bignell G.R., Cox C., Stephens P.J., Edkins S., Clegg S., Teague J.W., Woffendin H., Garnett M.J., Bottomley W., Davis N., Dicks E., Ewing R., Floyd Y., Gray K., Hall S., Hawes R., Hughes J., Kosmidou V., Menzies A., Mould C., Parker A., Stevens C., Watt S., Hooper S., Wilson R., Jayatilake H., Gusterson B.A., Cooper C.S., Shipley J.M., Hargrave D., Pritchard-Jones K., Maitland N.J., Chenevix-Trench G., Riggins G.J., Bigner D.D., Palmieri G., Cossu A., Flanagan A.M., Nicholson A., Ho J.W.C., Leung S.Y., Yuen S.T., Weber B.L., Seigler H.F., Darrow T.L., Paterson H.F., Marais R., Marshall C.J., Wooster R., Stratton M.R., Futreal P.A.
Mutations of the BRAF gene in human cancer.
Nature 417:949-954(2002)

Cross-references
Cell line databases/resources cancercelllines; CVCL_H580
Chemistry resources ChEMBL-Cells; CHEMBL3307709
ChEMBL-Targets; CHEMBL614798
PubChem_Cell_line; CVCL_H580
Encyclopedic resources Wikidata; Q54795836
Gene expression databases GEO; GSM1374398
GEO; GSM1374399
Polymorphism and mutation databases Cosmic; 724835
Entry history
Entry creation11-Feb-2013
Last entry update05-Oct-2023
Version number14