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Cellosaurus JB6 [Human anaplastic large cell lymphoma] (CVCL_H633)

[Text version]

Cell line name JB6 [Human anaplastic large cell lymphoma]
Synonyms JB-6; JB
Accession CVCL_H633
Resource Identification Initiative To cite this cell line use: JB6 [Human anaplastic large cell lymphoma] (RRID:CVCL_H633)
Comments Doubling time: 60 hours (CelloPub=CLPUB00058).
Derived from sampling site: Peripheral blood.
Sequence variations NPM1-ALK gene fusion (PubMed=15356658).
Disease Anaplastic large cell lymphoma, ALK-positive (NCIt: C37193)
ALK-positive anaplastic large cell lymphoma (ORDO: Orphanet_300895)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 12Y
Category Cancer cell line

Kadin M.E., Cavaille-Col M.W., Sioutos N., Fletcher J.A., Morton C.C., Pastuzak W., Rezuke W., Altman A.J.
Childhood Ki-1+ anaplastic large cell lymphoma: establishment and characterization of a new tumor cell line transplantable to SCID mice.
Blood 76 Suppl. 1:354a-354a(1990)

Dirks W.G., Zaborski M., Jager K., Challier C., Shiota M., Quentmeier H., Drexler H.G.
The (2;5)(p23;q35) translocation in cell lines derived from malignant lymphomas: absence of t(2;5) in Hodgkin-analogous cell lines.
Leukemia 10:142-149(1996)

PubMed=11021758; DOI=10.1038/sj.leu.2401891
Majka M., Rozmyslowicz T., Honczarenko M., Ratajczak J., Wasik M.A., Gaulton G.N., Ratajczak M.Z.
Biological significance of the expression of HIV-related chemokine coreceptors (CCR5 and CXCR4) and their ligands by human hematopoietic cell lines.
Leukemia 14:1821-1832(2000)

Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=15356658; DOI=10.1038/sj.leu.2403465
Drexler H.G., MacLeod R.A.F.
Malignant hematopoietic cell lines: in vitro models for the study of anaplastic large-cell lymphoma.
Leukemia 18:1569-1571(2004)

PubMed=17170727; DOI=10.1038/sj.leu.2404486
Sandberg Y., Verhaaf B., van Gastel-Mol E.J., Wolvers-Tettero I.L.M., de Vos J., Macleod R.A.F., Noordzij J.G., Dik W.A., van Dongen J.J.M., Langerak A.W.
Human T-cell lines with well-defined T-cell receptor gene rearrangements as controls for the BIOMED-2 multiplex polymerase chain reaction tubes.
Leukemia 21:230-237(2007)

Gene expression databases GEO; GSM1217150
Other Wikidata; Q54898522
Polymorphism and mutation databases Cosmic; 850200
Cosmic; 1086363
Entry history
Entry creation11-Feb-2013
Last entry update12-Mar-2020
Version number12