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Cellosaurus KBM-3/DOX (CVCL_H688)

[Text version]
Cell line name KBM-3/DOX
Accession CVCL_H688
Resource Identification Initiative To cite this cell line use: KBM-3/DOX (RRID:CVCL_H688)
Comments Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Adriamycin).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
Disease Acute myelomonocytic leukemia (NCIt: C7463)
Acute myelomonocytic leukemia (ORDO: Orphanet_517)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A425 (KBM-3)
Sex of cell Female
Age at sampling 32Y
Category Cancer cell line
Publications

PubMed=1995877; DOI=10.1021/jm00106a013
Farquhar D., Newman R.A., Zuckerman J.E., Andersson B.S.
Doxorubicin analogues incorporating chemically reactive substituents.
J. Med. Chem. 34:561-564(1991)

Cross-references
Cell line databases/resources cancercelllines; CVCL_H688
Chemistry resources ChEMBL-Cells; CHEMBL3307838
ChEMBL-Targets; CHEMBL613994
PubChem_Cell_line; CVCL_H688
Encyclopedic resources Wikidata; Q54899584
Entry history
Entry creation11-Feb-2013
Last entry update05-Oct-2023
Version number15