ID   J774.16
AC   CVCL_HA24
SY   J774 clone 16; J774 1.6; J774-1.6
DR   BCRJ; 0273
DR   Wikidata; Q54898486
RX   PubMed=3792703;
RX   PubMed=6252274;
RX   PubMed=6350185;
RX   PubMed=7045866;
CC   Characteristics: Has a marked increase in the ability to reduce nitroblue tetrazolium (NBT) after stimulation with PMA (PubMed=6252274).
CC   Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
CC   Cell type: Macrophage; CL=CL_0000235.
CC   Breed/subspecies: BALB/c.
DI   NCIt; C134780; Mouse reticulum cell sarcoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_4692 ! J774
SX   Female
AG   Adult
CA   Cancer cell line
DT   Created: 26-09-16; Last updated: 05-10-23; Version: 7
//
RX   PubMed=3792703; DOI=10.1111/j.1432-0436.1986.tb00568.x;
RA   Leenen P.J.M., Jansen A.M.A.C., van Ewijk W.;
RT   "Murine macrophage cell lines can be ordered in a linear
RT   differentiation sequence.";
RL   Differentiation 32:157-164(1986).
//
RX   PubMed=6252274; DOI=10.1084/jem.152.4.808;
RA   Damiani G., Kiyotaki C., Soeller W., Sasada M., Peisach J.,
RA   Bloom B.R.;
RT   "Macrophage variants in oxygen metabolism.";
RL   J. Exp. Med. 152:808-822(1980).
//
RX   PubMed=6350185; DOI=10.1128/iai.41.3.1322-1331.1983;
RA   Tanaka Y., Tanowitz H., Bloom B.R.;
RT   "Growth of Trypanosoma cruzi in a cloned macrophage cell line and in a
RT   variant defective in oxygen metabolism.";
RL   Infect. Immun. 41:1322-1331(1983).
//
RX   PubMed=7045866; DOI=10.1073/pnas.79.8.2584;
RA   Tanaka Y., Kiyotaki C., Tanowitz H., Bloom B.R.;
RT   "Reconstitution of a variant macrophage cell line defective in oxygen
RT   metabolism with a H2O2-generating system.";
RL   Proc. Natl. Acad. Sci. U.S.A. 79:2584-2588(1982).
//