|Cell line name||IMR-90/GFPdeltaRaf-1[YY]:ER|
|Resource Identification Initiative||To cite this cell line use: IMR-90/GFPdeltaRaf-1[YY]:ER (RRID:CVCL_HA48)|
|Comments||Characteristics: Transfected with a construct that is composed of EGFP at the N-terminus, the catalytic domain of RAF1 (with 340-DD-341) in the middle and the hormone-binding domain of ESR1 at the C-terminus. Protein kinase activity is activated by estrogen or analogs such as 4-hydroxy-tamoxifen.|
Transfected with: HGNC; 9829; RAF1 (catalytic domain with D-340 and D-341).
Transfected with: HGNC; 3467; ESR1 (hormone-binding domain).
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Derived from sampling site: Fetal lung.
|Species of origin||Homo sapiens (Human)
(NCBI Taxonomy: 9606)
|Hierarchy||Parent: CVCL_0347 (IMR-90)|
|Sex of cell||Female|
|Age at sampling||16FW|
|Category||Finite cell line|
|Last entry update||12-Mar-2020|