Cellosaurus IMR-90/GFPdeltaRaf-1[YY]:ER (CVCL_HA48)
Cell line name | IMR-90/GFPdeltaRaf-1[YY]:ER |
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Accession | CVCL_HA48 |
Resource Identification Initiative | To cite this cell line use: IMR-90/GFPdeltaRaf-1[YY]:ER (RRID:CVCL_HA48) |
Comments | Population: Caucasian. Characteristics: Transfected with a construct that is composed of EGFP at the N-terminus, the catalytic domain of RAF1 (with 340-DD-341) in the middle and the hormone-binding domain of ESR1 at the C-terminus. Protein kinase activity is activated by estrogen or analogs such as 4-hydroxy-tamoxifen. Transfected with: HGNC; 9829; RAF1 (catalytic domain with D-340 and D-341). Transfected with: HGNC; 3467; ESR1 (hormone-binding domain). Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP). Derived from site: In situ; Fetal lung; UBERON=UBERON_0005597. Cell type: Fibroblast of lung; CL=CL_0002553. |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_0347 (IMR-90) |
Sex of cell | Female |
Age at sampling | 16FW |
Category | Finite cell line |
Publications | PubMed=9765202; DOI=10.1101/gad.12.19.2997 |
Cross-references | |
Encyclopedic resources | Wikidata; Q54897673 |
Entry history | |
Entry creation | 26-Sep-2016 |
Last entry update | 05-Oct-2023 |
Version number | 11 |