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Cellosaurus HEP G2ins (CVCL_HA60)

[Text version]

Cell line name HEP G2ins
Synonyms HEPG2ins; HepG2ins
Accession CVCL_HA60
Resource Identification Initiative To cite this cell line use: HEP G2ins (RRID:CVCL_HA60)
Comments Transfected with: HGNC; 6081; INS.
Sequence variations NRAS p.Gln61Leu (c.182A>T) (ClinVar=VCV000375874) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
CVCL_HA61 (HEP G2ins/g)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line

Tuch B.E., Simpson A.M., Marshall G.M.
Transformed human hepatoma cell line which releases insulin.
Patent number WO1995032740A1, 07-Dec-1995

Simpson A.M., Tuch B.E., Swan M.A., Tu J., Marshall G.M.
Functional expression of the human insulin gene in a human hepatoma cell line (HEP G2).
Gene Ther. 2:223-231(1995)

PubMed=12958175; DOI=10.1096/fj.02-0051fje
Liu G.J., Simpson A.M., Swan M.A., Tao C., Tuch B.E., Crawford R.M., Jovanovic A., Martin D.K.
ATP-sensitive potassium channels induced in liver cells after transfection with insulin cDNA and the GLUT 2 transporter regulate glucose-stimulated insulin secretion.
FASEB J. 17:1682-1684(2003)

Other Wikidata; Q54882748
Entry history
Entry creation26-Sep-2016
Last entry update02-Jul-2020
Version number7