ID   CHO 7PA2
AC   CVCL_HC66
SY   CHO-7PA2; CHO7PA2; 7PA2
DR   Wikidata; Q54812555
RX   PubMed=7721886;
RX   PubMed=23948918;
RX   PubMed=24840308;
CC   Transfected with: HGNC; 620; APP (isoform APP751; with p.Val717Phe).
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_0214 ! CHO-K1
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 01-12-16; Last updated: 30-01-24; Version: 9
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RX   PubMed=7721886; DOI=10.1074/jbc.270.16.9564;
RA   Podlisny M.B., Ostaszewski B.L., Squazzo S.L., Koo E.H., Rydell R.E.,
RA   Teplow D.B., Selkoe D.J.;
RT   "Aggregation of secreted amyloid beta-protein into sodium dodecyl
RT   sulfate-stable oligomers in cell culture.";
RL   J. Biol. Chem. 270:9564-9570(1995).
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RX   PubMed=23948918; DOI=10.3233/JAD-130728;
RA   Krako N., Magnifico M.C., Arese M., Meli G., Forte E., Lecci A.,
RA   Manca A., Giuffre A., Mastronicola D., Sarti P., Cattaneo A.;
RT   "Characterization of mitochondrial dysfunction in the 7PA2 cell model
RT   of Alzheimer's disease.";
RL   J. Alzheimers Dis. 37:747-758(2013).
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RX   PubMed=24840308; DOI=10.1021/bi5003053;
RA   Welzel A.T., Maggio J.E., Shankar G.M., Walker D.E., Ostaszewski B.L.,
RA   Li S.-M., Klyubin I., Rowan M.J., Seubert P., Walsh D.M., Selkoe D.J.;
RT   "Secreted amyloid beta-proteins in a cell culture model include
RT   N-terminally extended peptides that impair synaptic plasticity.";
RL   Biochemistry 53:3908-3921(2014).
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