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Cellosaurus DLD-1 AKT2(-/-) (CVCL_HD53)

[Text version]
Cell line name DLD-1 AKT2(-/-)
Synonyms AKT2 (-/-) DLD-1
Accession CVCL_HD53
Resource Identification Initiative To cite this cell line use: DLD-1 AKT2(-/-) (RRID:CVCL_HD53)
Comments Population: Caucasian.
Knockout cell: Method=Homologous recombination; HGNC; 392; AKT2.
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0248 (DLD-1)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=20133737; DOI=10.1073/pnas.0914018107
Ericson K., Gan C., Cheong I., Rago C., Samuels Y., Velculescu V.E., Kinzler K.W., Huso D.L., Vogelstein B., Papadopoulos N.
Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation.
Proc. Natl. Acad. Sci. U.S.A. 107:2598-2603(2010)

PubMed=27878243; DOI=10.3892/ijo.2016.3771
Haggblad Sahlberg S., Mortensen A.C., Haglof J., Engskog M.K.R., Arvidsson T., Pettersson C., Glimelius B., Stenerlow B., Nestor M.
Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells.
Int. J. Oncol. 50:5-14(2017)

Cross-references
Cell line collections (Providers) Horizon_Discovery; HD+R00-002
Encyclopedic resources Wikidata; Q54831150
Entry history
Entry creation01-Dec-2016
Last entry update05-Oct-2023
Version number5