Cellosaurus KMS-11 WHSC1(trans/-) (CVCL_HE03)

Cell line name KMS-11 WHSC1(trans/-)
Synonyms WHSC1 (trans/-) KMS-11; KMS-11 MMSET Non-T-KO; KMS-11/NTKO; KMS11/NTKO; NTKO
Accession CVCL_HE03
Resource Identification Initiative To cite this cell line use: KMS-11 WHSC1(trans/-) (RRID:CVCL_HE03)
Comments Characteristics: Produces IgG kappa.
Characteristics: In KMS-11 one of the two WHSC1 alleles is translocated. This cell line is KO for the non-translocated allele.
Knockout cell: Method=Homologous recombination (1 of 2 alleles); HGNC; 12766; WHSC1.
Derived from sampling site: Pleural effusion.
Disease Plasma cell myeloma (NCIt: C3242)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2989 (KMS-11)
Sex of cell Female
Age at sampling 67Y
Category Cancer cell line
Web pages https://www.horizondiscovery.com/human-whsc1-trans-kms-11-cell-line-hd-108-001

PubMed=17942756; DOI=10.1182/blood-2007-05-088674
Lauring J., Abukhdeir A.M., Konishi H., Garay J.P., Gustin J.P., Wang Q., Arceci R.J., Matsui W., Park B.H.
The multiple myeloma associated MMSET gene contributes to cellular adhesion, clonogenic growth, and tumorigenicity.
Blood 111:856-864(2008)

Ontologies BTO; BTO:0005875