Cellosaurus RKO TP53(-/-) (CVCL_HE25)

Cell line name RKO TP53(-/-)
Synonyms TP53 (-/-) RKO
Accession CVCL_HE25
Resource Identification Initiative To cite this cell line use: RKO TP53(-/-) (RRID:CVCL_HE25)
Comments Knockout cell: Method=Recombinant Adeno-Associated Virus; HGNC; 11998; TP53.
Disease Colon carcinoma (NCIt: C4910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0504 (RKO)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Web pages https://www.horizondiscovery.com/human-tp53-rko-cell-line-hd-106-002

PubMed=19225112; DOI=10.1073/pnas.0813333106
Sur S., Pagliarini R., Bunz F., Rago C., Diaz L.A. Jr., Kinzler K.W., Vogelstein B., Papadopoulos N.
A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53.
Proc. Natl. Acad. Sci. U.S.A. 106:3964-3969(2009)