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Cellosaurus MIP/5FU (CVCL_HE61)

[Text version]
Cell line name MIP/5FU
Synonyms MIP/5-FU; MIP5FU
Accession CVCL_HE61
Resource Identification Initiative To cite this cell line use: MIP/5FU (RRID:CVCL_HE61)
Comments Selected for resistance to: ChEBI; CHEBI:46345; 5-fluorouracil (5-FU).
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Ser241Phe (c.722C>T); ClinVar=VCV000012359; Zygosity=Unspecified (from parent cell line).
HLA typing Source: PubMed=25960936
Class I
HLA-AA*24:02,02:01
HLA-BB*35:08,35:08
HLA-CC*07:01,04:01
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_H689 (MIP-101)
Sex of cell Male
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=15902309; DOI=10.1172/JCI23002
Tai I.T., Dai M., Owen D.A., Chen L.B.
Genome-wide expression analysis of therapy-resistant tumors reveals SPARC as a novel target for cancer therapy.
J. Clin. Invest. 115:1492-1502(2005)

PubMed=20835245; DOI=10.1038/nmeth.1503
Griffith M., Griffith O.L., Mwenifumbo J., Goya R., Morrissy A.S., Morin R.D., Corbett R., Tang M.J., Hou Y.-C., Pugh T.J., Robertson G., Chittaranjan S., Ally A., Asano J.K., Chan S.Y., Li H.-Y.I., McDonald H., Teague K., Zhao Y.-J., Zeng T., Delaney A., Hirst M., Morin G.B., Jones S.J.M., Tai I.T., Marra M.A.
Alternative expression analysis by RNA sequencing.
Nat. Methods 7:843-847(2010)

PubMed=25960936; DOI=10.4161/21624011.2014.954893
Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:e954893.1-e954893.12(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_HE61
Encyclopedic resources Wikidata; Q54905752
Gene expression databases GEO; GSM587039
Entry history
Entry creation01-Dec-2016
Last entry update05-Oct-2023
Version number10