ID   HepG2T14
SY   HepG2T-14
DR   Wikidata; Q54882864
RX   PubMed=3019565;
RX   PubMed=9755253;
CC   Population: Caucasian.
CC   Characteristics: This cell line has been transfected with a circular HBV.
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
CC   Derived from sampling site: Liver.
DI   NCIt; C3728; Hepatoblastoma
DI   ORDO; Orphanet_449; Hepatoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0027 ! Hep-G2
SX   Male
AG   15Y
CA   Cancer cell line
DT   Created: 01-12-16; Last updated: 20-05-21; Version: 10
RX   PubMed=3019565; DOI=10.1016/0092-8674(86)90364-8;
RA   Sureau C., Romet-Lemonne J.-L., Mullins J.I., Essex M.;
RT   "Production of hepatitis B virus by a differentiated human hepatoma
RT   cell line after transfection with cloned circular HBV DNA.";
RL   Cell 47:37-47(1986).
RX   PubMed=9755253; DOI=10.1002/hep.510280431;
RA   Roingeard P., Sureau C.;
RT   "Ultrastructural analysis of hepatitis B virus in HepG2-transfected
RT   cells with special emphasis on subviral filament morphogenesis.";
RL   Hepatology 28:1128-1133(1998).