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Cellosaurus Sdhb-/- CL 7 (CVCL_HG13)

[Text version]

Cell line name Sdhb-/- CL 7
Synonyms Sdhb -/- CL 7
Accession CVCL_HG13
Resource Identification Initiative To cite this cell line use: Sdhb-/- CL 7 (RRID:CVCL_HG13)
Comments Knockout cell: Method=Cre/loxP; MGI; MGI:1914930; Sdhb.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6Ncr x 129S6/SvEvTac.
Hierarchy Parent: CVCL_HG11 (Sdhb fl/fl)
Sex of cell Male
Age at sampling Blastocyst stage
Category Transformed cell line
Publications

PubMed=26302408; DOI=10.1038/ncb3233
Cardaci S., Zheng L., MacKay G., van den Broek N.J.F., MacKenzie E.D., Nixon C., Stevenson D., Tumanov S., Bulusu V., Kamphorst J.J., Vazquez A., Fleming S., Schiavi F., Kalna G., Blyth K., Strathdee D., Gottlieb E.
Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.
Nat. Cell Biol. 17:1317-1326(2015)

Cross-references
Cell line collections CancerTools; 153293
Ximbio; 153293
Encyclopedic resources Wikidata; Q54952717
Entry history
Entry creation01-Dec-2016
Last entry update23-Jun-2022
Version number5