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Cellosaurus T47D-E2J (CVCL_HG14)

[Text version]

Cell line name T47D-E2J
Synonyms T47D E2J; E2J
Accession CVCL_HG14
Resource Identification Initiative To cite this cell line use: T47D-E2J (RRID:CVCL_HG14)
Comments Transfected with: HGNC; 4203; GCNT1.
Sequence variations Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Leu194Phe (c.580C>T); ClinVar=VCV000127817; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0553 (T-47D)
Children:
CVCL_HG16 (T47D-StN)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=11118434; DOI=10.1074/jbc.M006523200
Dalziel M., Whitehouse C., McFarlane I., Brockhausen I., Gschmeissner S., Schwientek T., Clausen H., Burchell J.M., Taylor-Papadimitriou J.
The relative activities of the C2GnT1 and ST3Gal-I glycosyltransferases determine O-glycan structure and expression of a tumor-associated epitope on MUC1.
J. Biol. Chem. 276:11007-11015(2001)

PubMed=16319059; DOI=10.1074/jbc.M511826200
Sewell R., Backstrom M., Dalziel M., Gschmeissner S., Karlsson H., Noll T., Gatgens J., Clausen H., Hansson G.C., Burchell J.M., Taylor-Papadimitriou J.
The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer.
J. Biol. Chem. 281:3586-3594(2006)

Cross-references
Cell line collections Ximbio; 153169
Other Wikidata; Q54971560
Entry history
Entry creation01-Dec-2016
Last entry update20-May-2021
Version number8