| Cell line name |
T47D-E2J |
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| Synonyms |
T47D E2J; E2J |
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| Accession |
CVCL_HG14 |
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| Resource Identification Initiative |
To cite this cell line use: T47D-E2J (RRID:CVCL_HG14) |
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| Comments |
Population: Caucasian.
Transfected with: HGNC; 4203; GCNT1.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175. |
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| Sequence variations |
- Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Leu194Phe (c.580C>T); ClinVar=VCV000127817; Zygosity=Homozygous (from parent cell line).
|
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| Disease |
Invasive breast carcinoma of no special type (NCIt: C4194) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_0553 (T-47D)
Children:
|
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| Sex of cell |
Female |
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| Age at sampling |
54Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=11118434; DOI=10.1074/jbc.M006523200
Dalziel M., Whitehouse C., McFarlane I., Brockhausen I., Gschmeissner S., Schwientek T., Clausen H., Burchell J.M., Taylor-Papadimitriou J.
The relative activities of the C2GnT1 and ST3Gal-I glycosyltransferases determine O-glycan structure and expression of a tumor-associated epitope on MUC1.
J. Biol. Chem. 276:11007-11015(2001) PubMed=16319059; DOI=10.1074/jbc.M511826200
Sewell R., Backstrom M., Dalziel M., Gschmeissner S., Karlsson H., Noll T., Gatgens J., Clausen H., Hansson G.C., Burchell J.M., Taylor-Papadimitriou J.
The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer.
J. Biol. Chem. 281:3586-3594(2006) |
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| Cross-references |
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| Cell line collections (Providers) |
CancerTools; 153169
Ximbio; 153169
|
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| Cell line databases/resources |
cancercelllines; CVCL_HG14
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| Encyclopedic resources |
Wikidata; Q54971560
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| Entry history |
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| Entry creation | 01-Dec-2016 |
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| Last entry update | 05-Oct-2023 |
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| Version number | 12 |
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