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Cellosaurus BCN (CVCL_HX06)

[Text version]

Cell line name BCN
Accession CVCL_HX06
Resource Identification Initiative To cite this cell line use: BCN (RRID:CVCL_HX06)
Comments Characteristics: Produces IgG kappa.
Characteristics: IL6 dependent.
Omics: Deep exome analysis.
Omics: Transcriptome analysis.
Miscellaneous: HLA typing from personal communication of Pellat-Deceunynck C.
Derived from sampling site: Peripheral blood.
HLA typing Source: Direct_author_submission
Class I
HLA-AA*11,26
HLA-BB*13,27
HLA-CC*02:02,06:02
Disease Plasma cell myeloma (NCIt: C3242)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=10583232; DOI=10.1046/j.1365-2141.1999.01705.x
Puthier D., Derenne S., Barille S., Moreau P., Harousseau J.-L., Bataille R., Amiot M.
Mcl-1 and Bcl-xL are co-regulated by IL-6 in human myeloma cells.
Br. J. Haematol. 107:392-395(1999)

PubMed=16956823
Bataille R., Jego G., Robillard N., Barille-Nion S., Harousseau J.-L., Moreau P., Amiot M., Pellat-Deceunynck C.
The phenotype of normal, reactive and malignant plasma cells Identification of 'many and multiple myelomas' and of new targets for myeloma therapy.
Haematologica 91:1234-1240(2006)

PubMed=21173094; DOI=10.3324/haematol.2010.033456
Moreaux J., Klein B., Bataille R., Descamps G., Maiga S., Hose D., Goldschmidt H., Jauch A., Reme T., Jourdan M., Amiot M., Pellat-Deceunynck C.
A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines.
Haematologica 96:574-582(2011)

PubMed=30545397; DOI=10.1186/s13045-018-0679-0
Tessoulin B., Moreau-Aubry A., Descamps G., Gomez-Bougie P., Maiga S., Gaignard A., Chiron D., Menoret E., Le Gouill S., Moreau P., Amiot M., Pellat-Deceunynck C.
Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways.
J. Hematol. Oncol. 11:137-137(2018)

Cross-references
Gene expression databases ArrayExpress; E-TABM-1088
Other Wikidata; Q54795699
Entry history
Entry creation01-Dec-2016
Last entry updated05-Jul-2019
Version number5