ID   SBN
AC   CVCL_HX10
SY   SBN-1
DR   ArrayExpress; E-TABM-1088
DR   IARC_TP53; 28501
DR   Wikidata; Q54952216
RX   PubMed=10100725;
RX   PubMed=10583232;
RX   PubMed=16956823;
RX   PubMed=21173094;
WW   https://www.keatslab.org/myeloma-cell-lines/hmcl-characteristics
CC   Characteristics: IL6 dependent.
CC   HLA typing: A*02:01,32:01; B*14:02,57; C*06:02,08:02 (Direct_author_submission).
CC   Omics: Transcriptome analysis by microarray.
CC   Miscellaneous: HLA typing from personal communication of Pellat-Deceunynck C.
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C3242; Plasma cell myeloma
DI   ORDO; Orphanet_29073; Multiple myeloma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 01-12-16; Last updated: 29-06-23; Version: 9
//
RX   PubMed=10100725;
RA   Pellat-Deceunynck C., Jego G., Harousseau J.-L., Vie H., Bataille R.;
RT   "Isolation of human lymphocyte antigens class I-restricted cytotoxic T
RT   lymphocytes against autologous myeloma cells.";
RL   Clin. Cancer Res. 5:705-709(1999).
//
RX   PubMed=10583232; DOI=10.1046/j.1365-2141.1999.01705.x;
RA   Puthier D., Derenne S., Barille S., Moreau P., Harousseau J.-L.,
RA   Bataille R., Amiot M.;
RT   "Mcl-1 and Bcl-xL are co-regulated by IL-6 in human myeloma cells.";
RL   Br. J. Haematol. 107:392-395(1999).
//
RX   PubMed=16956823;
RA   Bataille R., Jego G., Robillard N., Barille-Nion S., Harousseau J.-L.,
RA   Moreau P., Amiot M., Pellat-Deceunynck C.;
RT   "The phenotype of normal, reactive and malignant plasma cells.
RT   Identification of 'many and multiple myelomas' and of new targets for
RT   myeloma therapy.";
RL   Haematologica 91:1234-1240(2006).
//
RX   PubMed=21173094; DOI=10.3324/haematol.2010.033456;
RA   Moreaux J., Klein B., Bataille R., Descamps G., Maiga S., Hose D.,
RA   Goldschmidt H., Jauch A., Reme T., Jourdan M., Amiot M.,
RA   Pellat-Deceunynck C.;
RT   "A high-risk signature for patients with multiple myeloma established
RT   from the molecular classification of human myeloma cell lines.";
RL   Haematologica 96:574-582(2011).
//