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Cellosaurus XG-10 (CVCL_HX11)

[Text version]

Cell line name XG-10
Synonyms XG10
Accession CVCL_HX11
Resource Identification Initiative To cite this cell line use: XG-10 (RRID:CVCL_HX11)
Comments Characteristics: IL6 dependent.
Omics: Deep exome analysis.
Omics: Transcriptome analysis.
Miscellaneous: HLA typing from personal communication of Pellat-Deceunynck C.
Derived from sampling site: Ascites.
Sequence variations Has no TP53 mutation (PubMed=21173094).
HLA typing Source: Direct_author_submission
Class I
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
Web pages https://www.keatslab.org/myeloma-cell-lines/hmcl-characteristics

PubMed=10557056; DOI=10.1038/sj.leu.2401563
Yoshida S., Nakazawa N., Iida S., Hayami Y., Sato S., Wakita A., Shimizu S., Taniwaki M., Ueda R.
Detection of MUM1/IRF4-IgH fusion in multiple myeloma.
Leukemia 13:1812-1816(1999)

PubMed=19718049; DOI=10.1038/onc.2009.257
Seckinger A., Meissner T., Moreaux J., Goldschmidt H., Fuhler G.M., Benner A., Hundemer M., Reme T., Shaughnessy J.D. Jr., Barlogie B., Bertsch U., Hillengass J., Ho A.D., Pantesco V., Jauch A., De Vos J., Rossi J.F., Mohler T., Klein B., Hose D.
Bone morphogenic protein 6: a member of a novel class of prognostic factors expressed by normal and malignant plasma cells inhibiting proliferation and angiogenesis.
Oncogene 28:3866-3879(2009)

PubMed=21173094; DOI=10.3324/haematol.2010.033456
Moreaux J., Klein B., Bataille R., Descamps G., Maiga S., Hose D., Goldschmidt H., Jauch A., Reme T., Jourdan M., Amiot M., Pellat-Deceunynck C.
A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines.
Haematologica 96:574-582(2011)

PubMed=30545397; DOI=10.1186/s13045-018-0679-0
Tessoulin B., Moreau-Aubry A., Descamps G., Gomez-Bougie P., Maiga S., Gaignard A., Chiron D., Menoret E., Le Gouill S., Moreau P., Amiot M., Pellat-Deceunynck C.
Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways.
J. Hematol. Oncol. 11:137-137(2018)

Gene expression databases ArrayExpress; E-TABM-1088
Other Wikidata; Q54994695
Polymorphism and mutation databases IARC_TP53; 28491
Entry history
Entry creation01-Dec-2016
Last entry updated12-Mar-20
Version number5