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Cellosaurus XG-11 (CVCL_HX12)

[Text version]

Cell line name XG-11
Synonyms XG11
Accession CVCL_HX12
Resource Identification Initiative To cite this cell line use: XG-11 (RRID:CVCL_HX12)
Comments Characteristics: Produces Ig lambda.
Characteristics: IL6 dependent.
Omics: Deep exome analysis.
Omics: Transcriptome analysis.
Miscellaneous: HLA typing from personal communication of Pellat-Deceunynck C.
Derived from sampling site: Peripheral blood.
Sequence variations TP53 p.Cys135Tyr (c.404G>A) (PubMed=21173094).
HLA typing Source: Direct_author_submission
Class I
Disease Plasma cell myeloma (NCIt: C3242)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line

PubMed=19718049; DOI=10.1038/onc.2009.257
Seckinger A., Meissner T., Moreaux J., Goldschmidt H., Fuhler G.M., Benner A., Hundemer M., Reme T., Shaughnessy J.D. Jr., Barlogie B., Bertsch U., Hillengass J., Ho A.D., Pantesco V., Jauch A., De Vos J., Rossi J.F., Mohler T., Klein B., Hose D.
Bone morphogenic protein 6: a member of a novel class of prognostic factors expressed by normal and malignant plasma cells inhibiting proliferation and angiogenesis.
Oncogene 28:3866-3879(2009)

PubMed=21173094; DOI=10.3324/haematol.2010.033456
Moreaux J., Klein B., Bataille R., Descamps G., Maiga S., Hose D., Goldschmidt H., Jauch A., Reme T., Jourdan M., Amiot M., Pellat-Deceunynck C.
A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines.
Haematologica 96:574-582(2011)

PubMed=30545397; DOI=10.1186/s13045-018-0679-0
Tessoulin B., Moreau-Aubry A., Descamps G., Gomez-Bougie P., Maiga S., Gaignard A., Chiron D., Menoret E., Le Gouill S., Moreau P., Amiot M., Pellat-Deceunynck C.
Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways.
J. Hematol. Oncol. 11:137-137(2018)

Gene expression databases ArrayExpress; E-TABM-1088
Other Wikidata; Q54994696
Polymorphism and mutation databases IARC_TP53; 28502
Entry history
Entry creation01-Dec-2016
Last entry updated05-Jul-2019
Version number5