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Cellosaurus XG-16 (CVCL_HX16)

[Text version]
Cell line name XG-16
Synonyms XG16
Accession CVCL_HX16
Resource Identification Initiative To cite this cell line use: XG-16 (RRID:CVCL_HX16)
Comments Characteristics: Produces Ig kappa.
Characteristics: IL6 dependent.
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Miscellaneous: HLA typing from personal communication of Pellat-Deceunynck C.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
HLA typing Source: Direct_author_submission
Class I
HLA-AA*02,29
HLA-BB*40,49
HLA-CC*02,07
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
Web pages https://www.keatslab.org/myeloma-cell-lines/hmcl-characteristics
Publications

PubMed=21173094; DOI=10.3324/haematol.2010.033456
Moreaux J., Klein B., Bataille R., Descamps G., Maiga S., Hose D., Goldschmidt H., Jauch A., Reme T., Jourdan M., Amiot M., Pellat-Deceunynck C.
A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines.
Haematologica 96:574-582(2011)

PubMed=30545397; DOI=10.1186/s13045-018-0679-0
Tessoulin B., Moreau-Aubry A., Descamps G., Gomez-Bougie P., Maiga S., Gaignard A., Chiron D., Menoret E., Le Gouill S., Moreau P., Amiot M., Pellat-Deceunynck C.
Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways.
J. Hematol. Oncol. 11:137.1-137.13(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_HX16
Encyclopedic resources Wikidata; Q54994701
Gene expression databases ArrayExpress; E-TABM-1088
Polymorphism and mutation databases Cosmic; 2809776
IARC_TP53; 28499
Entry history
Entry creation01-Dec-2016
Last entry update05-Oct-2023
Version number12