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Cellosaurus XG-16 (CVCL_HX16)

[Text version]

Cell line name XG-16
Synonyms XG16
Accession CVCL_HX16
Resource Identification Initiative To cite this cell line use: XG-16 (RRID:CVCL_HX16)
Comments Characteristics: Produces Ig kappa.
Characteristics: IL6 dependent.
Omics: Deep exome analysis.
Omics: Transcriptome analysis.
Miscellaneous: HLA typing from personal communication of Pellat-Deceunynck C.
Derived from sampling site: Peripheral blood.
Sequence variations NRAS p.Gln61His (c.183A>C) (PubMed=21173094).
TP53 p.Tyr220Cys (c.659A>G) (PubMed=21173094).
HLA typing Source: Direct_author_submission
Class I
HLA-AA*02,29
HLA-BB*40,49
HLA-CC*02,07
Disease Plasma cell myeloma (NCIt: C3242)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
Publications

PubMed=21173094; DOI=10.3324/haematol.2010.033456
Moreaux J., Klein B., Bataille R., Descamps G., Maiga S., Hose D., Goldschmidt H., Jauch A., Reme T., Jourdan M., Amiot M., Pellat-Deceunynck C.
A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines.
Haematologica 96:574-582(2011)

PubMed=30545397; DOI=10.1186/s13045-018-0679-0
Tessoulin B., Moreau-Aubry A., Descamps G., Gomez-Bougie P., Maiga S., Gaignard A., Chiron D., Menoret E., Le Gouill S., Moreau P., Amiot M., Pellat-Deceunynck C.
Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways.
J. Hematol. Oncol. 11:137-137(2018)

Cross-references
Gene expression databases ArrayExpress; E-TABM-1088
Other Wikidata; Q54994701
Polymorphism and mutation databases IARC_TP53; 28499
Entry history
Entry creation01-Dec-2016
Last entry updated05-Jul-2019
Version number5