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Cellosaurus BIONi010-C-4 (CVCL_II83)

[Text version]

Cell line name BIONi010-C-4
Synonyms BIONi010-C ApoE E4/E4 #B44 P27
Accession CVCL_II83
Resource Identification Initiative To cite this cell line use: BIONi010-C-4 (RRID:CVCL_II83)
Comments From: Bioneer A/S; Denmark.
Omics: Genome sequenced.
Derived from sampling site: Skin.
Sequence variations Homozygous for APOE p.Cys130Arg (c.388T>C) (ClinVar=VCV000017864); Note=ApoE4 allele; by CRISPR/Cas9 (PubMed=30660866).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1E68 (BIONi010-C)
Sex of cell Male
Age at sampling 18Y
Category Induced pluripotent stem cell

PubMed=30660866; DOI=10.1016/j.scr.2018.11.010
Schmid B., Prehn K.R., Nimsanor N., Garcia B.I.A., Poulsen U., Jorring I., Rasmussen M.A., Clausen C., Mau-Holzmann U.A., Ramakrishna S., Muddashetty R., Steeg R., Bruce K., Mackintosh P., Ebneth A., Holst B., Cabrera-Socorro A.
Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line.
Stem Cell Res. 34:101349-101349(2019)

Cell line collections EBiSC; BIONi010-C-4
ECACC; 66540366
Cell line databases/resources hPSCreg; BIONi010-C-4
SKIP; SKIP002853
Biological sample resources BioSamples; SAMEA4452060
Other Wikidata; Q54796774
Entry history
Entry creation01-Dec-2016
Last entry update12-Jan-2021
Version number8