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Cellosaurus BIONi010-C-6 (CVCL_II85)

[Text version]

Cell line name BIONi010-C-6
Synonyms BIONi010-C ApoE E2/E2
Accession CVCL_II85
Resource Identification Initiative To cite this cell line use: BIONi010-C-6 (RRID:CVCL_II85)
Comments From: Bioneer A/S; Denmark.
Population: African.
Omics: Genome sequenced.
Derived from sampling site: Skin.
Sequence variations Mutation; HGNC; 613; APOE; Simple_edited; p.Arg176Cys (c.526C>T); ClinVar=VCV000017848; Zygosity=Homozygous; Note=ApoE2 allele. By CRISPR/Cas9. The second allele is disrupted by a 3.4 kb insertion from the selection plasmid (PubMed=30660866; PubMed=32971461).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1E68 (BIONi010-C)
Sex of cell Male
Age at sampling 18Y
Category Induced pluripotent stem cell
Publications

PubMed=30660866; DOI=10.1016/j.scr.2018.11.010
Schmid B., Prehn K.R., Nimsanor N., Garcia B.I.A., Poulsen U., Jorring I., Rasmussen M.A., Clausen C., Mau-Holzmann U.A., Ramakrishna S., Muddashetty R., Steeg R., Bruce K., Mackintosh P., Ebneth A., Holst B., Cabrera-Socorro A.
Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line.
Stem Cell Res. 34:101349-101349(2019)

PubMed=32971461; DOI=10.1016/j.scr.2020.102005
Schmid B., Prehn K.R., Nimsanor N., Garcia B.I.A., Poulsen U., Jorring I., Rasmussen M.A., Clausen C., Mau-Holzmann U.A., Ramakrishna S., Muddashetty R., Steeg R., Bruce K., Mackintosh P., Ebneth A., Holst B., Cabrera-Socorro A.
Corrigendum to 'Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line' [Stem Cell Res. 34/1873-5061 (2019) 101349-55].
Stem Cell Res. 48:102005-102005(2020)

Cross-references
Cell line collections EBiSC; BIONi010-C-6
ECACC; 66540368
Cell line databases/resources hPSCreg; BIONi010-C-6
SKIP; SKIP002861
Biological sample resources BioSamples; SAMEA4454009
Other Wikidata; Q54796778
Entry history
Entry creation01-Dec-2016
Last entry update20-May-2021
Version number10