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Cellosaurus UOXFi004-B (CVCL_IJ08)

[Text version]

Cell line name UOXFi004-B
Synonyms iPS-OX1-19; OX1-19; iPSc clone 19 from OX1 fibroblasts; Ctrl 2#1
Accession CVCL_IJ08
Resource Identification Initiative To cite this cell line use: UOXFi004-B (RRID:CVCL_IJ08)
Comments From: University of Oxford; Oxford; United Kingdom.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Skin; dermis. Cell type=Fibroblast.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A8Y7 (OX1)
Sex of cell Male
Age at sampling 36Y
Category Induced pluripotent stem cell
Publications

PubMed=23951090; DOI=10.1371/journal.pone.0071098
van Wilgenburg B., Browne C., Vowles J., Cowley S.A.
Efficient, long term production of monocyte-derived macrophages from human pluripotent stem cells under partly-defined and fully-defined conditions.
PLoS ONE 8:E71098-E71098(2013)

PubMed=26905200; DOI=10.1016/j.stemcr.2016.01.013
Fernandes H.J.R., Hartfield E.M., Christian H.C., Emmanoulidou E., Zheng Y., Booth H., Bogetofte H., Lang C., Ryan B.J., Sardi S.P., Badger J., Vowles J., Evetts S., Tofaris G.K., Vekrellis K., Talbot K., Hu M.T., James W., Cowley S.A., Wade-Martins R.
ER stress and autophagic perturbations lead to elevated extracellular alpha-synuclein in GBA-N370S Parkinson's iPSC-derived dopamine neurons.
Stem Cell Reports 6:342-356(2016)

PubMed=28096185; DOI=10.1093/hmg/ddw412
Sandor C., Robertson P., Lang C., Heger A., Booth H., Vowles J., Witty L., Bowden R., Hu M.T., Cowley S.A., Wade-Martins R., Webber C.
Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease.
Hum. Mol. Genet. 26:552-566(2017)

PubMed=30503143; DOI=10.1016/j.stem.2018.10.023
Lang C., Campbell K.R., Ryan B.J., Carling P., Attar M., Vowles J., Perestenko O.V., Bowden R., Baig F., Kasten M., Hu M.T., Cowley S.A., Webber C., Wade-Martins R.
Single-cell sequencing of iPSC-dopamine neurons reconstructs disease progression and identifies HDAC4 as a regulator of Parkinson cell phenotypes.
Cell Stem Cell 24:93-106.e6(2019)

Cross-references
Cell line collections EBiSC; UOXFi004-B - Discontinued
ECACC; 66540394
Cell line databases/resources hPSCreg; UOXFi004-B
Biological sample resources BioSamples; SAMEA4454111
Encyclopedic resources Wikidata; Q54991444
Gene expression databases GEO; GSM1105118
GEO; GSM1105122
Entry history
Entry creation01-Dec-2016
Last entry update17-Mar-2022
Version number8