ID   UOXFi004-B
AC   CVCL_IJ08
SY   iPS-OX1-19; OX1-19; iPSc clone 19 from OX1 fibroblasts; Ctrl 2#1
DR   BioSamples; SAMEA4454111
DR   EBiSC; UOXFi004-B
DR   ECACC; 66540394
DR   GEO; GSM1105118
DR   GEO; GSM1105122
DR   hPSCreg; UOXFi004-B
DR   Wikidata; Q54991444
RX   PubMed=23951090;
RX   PubMed=26905200;
RX   PubMed=28096185;
RX   PubMed=30503143;
CC   From: University of Oxford; Oxford; United Kingdom.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Discontinued: EBiSC; UOXFi004-B; true.
CC   Discontinued: ECACC; 66540394; true.
CC   Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_A8Y7 ! OX1
SX   Male
AG   36Y
CA   Induced pluripotent stem cell
DT   Created: 01-12-16; Last updated: 30-01-24; Version: 11
//
RX   PubMed=23951090; DOI=10.1371/journal.pone.0071098;
RA   van Wilgenburg B., Browne C., Vowles J., Cowley S.A.;
RT   "Efficient, long term production of monocyte-derived macrophages from
RT   human pluripotent stem cells under partly-defined and fully-defined
RT   conditions.";
RL   PLoS ONE 8:E71098-E71098(2013).
//
RX   PubMed=26905200; DOI=10.1016/j.stemcr.2016.01.013;
RA   Fernandes H.J.R., Hartfield E.M., Christian H.C., Emmanoulidou E.,
RA   Zheng Y., Booth H., Bogetofte H., Lang C., Ryan B.J., Sardi S.P.,
RA   Badger J., Vowles J., Evetts S., Tofaris G.K., Vekrellis K.,
RA   Talbot K., Hu M.T., James W., Cowley S.A., Wade-Martins R.;
RT   "ER stress and autophagic perturbations lead to elevated extracellular
RT   alpha-synuclein in GBA-N370S Parkinson's iPSC-derived dopamine
RT   neurons.";
RL   Stem Cell Reports 6:342-356(2016).
//
RX   PubMed=28096185; DOI=10.1093/hmg/ddw412;
RA   Sandor C., Robertson P., Lang C., Heger A., Booth H., Vowles J.,
RA   Witty L., Bowden R., Hu M.T., Cowley S.A., Wade-Martins R., Webber C.;
RT   "Transcriptomic profiling of purified patient-derived dopamine neurons
RT   identifies convergent perturbations and therapeutics for Parkinson's
RT   disease.";
RL   Hum. Mol. Genet. 26:552-566(2017).
//
RX   PubMed=30503143; DOI=10.1016/j.stem.2018.10.023;
RA   Lang C., Campbell K.R., Ryan B.J., Carling P.J., Attar M., Vowles J.,
RA   Perestenko O.V., Bowden R., Baig F., Kasten M., Hu M.T., Cowley S.A.,
RA   Webber C., Wade-Martins R.;
RT   "Single-cell sequencing of iPSC-dopamine neurons reconstructs disease
RT   progression and identifies HDAC4 as a regulator of Parkinson cell
RT   phenotypes.";
RL   Cell Stem Cell 24:93-106.e6(2019).
//