Cellosaurus MCF-7/TAX (CVCL_IJ26)

Cell line name MCF-7/TAX
Accession CVCL_IJ26
Resource Identification Initiative To cite this cell line use: MCF-7/TAX (RRID:CVCL_IJ26)
Comments Doubling time: 44.60 +- 1 hours (PubMed=24289639).
Selected for resistance to: ChEBI; CHEBI:45863; Paclitaxel (Taxol).
Sequence variations Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (from parent cell line).
Disease Invasive ductal carcinoma, not otherwise specified (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=24289639; DOI=10.7314/APJCP.2013.14.10.6135
Chen S.-Y., Hu S.-S., Dong Q., Cai J.-X., Zhang W.-P., Sun J.-Y., Wang T.-T., Xie J., He H.-R., Xing J.-F., Lu J., Dong Y.-L.
Establishment of paclitaxel-resistant breast cancer cell line and nude mice models, and underlying multidrug resistance mechanisms in vitro and in vivo.
Asian Pac. J. Cancer Prev. 14:6135-6140(2013)

Cross-references
Other Wikidata; Q54904385