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Cellosaurus haNK (CVCL_IM23)

[Text version]

Cell line name haNK
Synonyms high affinity NK; CD16-V158.NK-92.05
Accession CVCL_IM23
Resource Identification Initiative To cite this cell line use: haNK (RRID:CVCL_IM23)
Comments Characteristics: No longer dependent on IL2.
Transfected with: HGNC; 3619; FCGR3A (with p.Phe176Val).
Transfected with: HGNC; 6001; IL2.
Caution: This cell line is exclusively owned and controlled by NantKwest, Inc. NantKwest and its affiliate, Brink Biologics, Inc. are the sole authorized distributors for both commercial and non-commercial research requestors. There are no other authorized commercial and non-commercial suppliers for this cell line. Contact NantKwest and Brink Biologics for information concerning current inventory and cell line use and support.
Derived from sampling site: Peripheral blood. Cell type=Natural killer cell.
Disease Natural killer cell lymphoblastic leukemia/lymphoma (NCIt: C82217)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2142 (NK-92)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
Web pages https://brinkbiologics.com/platform/

PubMed=27861156; DOI=10.18632/oncotarget.13411
Jochems C., Hodge J.W., Fantini M., Fujii R., Morillon Y.M. II, Greiner J.W., Padget M.R., Tritsch S.R., Tsang K.Y., Campbell K.S., Klingemann H.-G., Boissel L., Rabizadeh S., Soon-Shiong P., Schlom J.
An NK cell line (haNK) expressing high levels of granzyme and engineered to express the high affinity CD16 allele.
Oncotarget 7:86359-86373(2016)

Encyclopedic resources Wikidata; Q54872409
Entry history
Entry creation01-Dec-2016
Last entry update16-Dec-2021
Version number6