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Cellosaurus K562 HHT (CVCL_IM25)

[Text version]

Cell line name K562 HHT
Synonyms K562-HHT
Accession CVCL_IM25
Resource Identification Initiative To cite this cell line use: K562 HHT (RRID:CVCL_IM25)
Comments Selected for resistance to: ChEBI; CHEBI:71019; Omacetaxine mepesuccinate (Homoharringtonine; HHT).
Derived from sampling site: Pleural effusion.
Sequence variations BCR-ABL1 gene fusion (from parent cell line).
Homozygous for TP53 p.Gln136fs*13 (c.406_407insC) (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line

Han J.-L., Yan W.-W., Qian Q.-J., Shi H., Han M.-Z., Qiu L.-G., Feng S.
Two homoharringtonine resistant leukemic cell lines (K562 HHT and L1210 HHT): establishment, characterization and mechanisms of action.
Zhonghua Yi Xue Za Zhi 74:424-427(1994)

Other Wikidata; Q54899376
Entry history
Entry creation01-Dec-2016
Last entry update12-Mar-2020
Version number8