Cellosaurus SKVCR2.0 (CVCL_IN09)

Cell line name SKVCR2.0
Synonyms SKVCR 2.0; SK VCR 2
Accession CVCL_IN09
Resource Identification Initiative To cite this cell line use: SKVCR2.0 (RRID:CVCL_IN09)
Comments Selected for resistance to: ChEBI; CHEBI:28445; Vincristine (VCR).
Sequence variation: Heterozygous for APC p.Thr1556fs*9 (from parent cell line).
Sequence variation: Heterozygous for PIK3CA p.His1047Arg (from parent cell line).
Sequence variation: Homozygous for TP53 p.Ser90fs*33 (from parent cell line).
Omics: Transcriptome analysis.
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Derived from metastatic site: Ascites.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0532 (SK-OV-3)
Sex of cell Female
Category Cancer cell line

Bradley G., Naik M., Ling V.
P-glycoprotein expression in multidrug-resistant human ovarian carcinoma cell lines.
Cancer Res. 49:2790-2796(1989)

PubMed=17726699; DOI=10.1002/gcc.20492
Buys T.P.H., Chari R., Lee E.H.L., Zhang M., MacAulay C., Lam S., Lam W.L., Ling V.
Genetic changes in the evolution of multidrug resistance for cultured human ovarian cancer cells.
Genes Chromosomes Cancer 46:1069-1079(2007)

Gene expression databases GEO; GSM183342
GEO; GSM183344