Cellosaurus SKVCR2.0 (CVCL_IN09)

Cell line name SKVCR2.0
Synonyms SKVCR 2.0; SK VCR 2
Accession CVCL_IN09
Resource Identification Initiative To cite this cell line use: SKVCR2.0 (RRID:CVCL_IN09)
Comments Selected for resistance to: ChEBI; CHEBI:28445; Vincristine (VCR).
Omics: Transcriptome analysis.
Sequence variations Heterozygous for PC p.Thr1556fs*9 (c.4666delA) (from parent cell line).
Heterozygous for PIK3CA p.His1047Arg (c.3140A>G) (from parent cell line).
Homozygous for TP53 p.Ser90fs*33 (c.267delC) (from parent cell line).
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Derived from metastatic site: Ascites.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0532 (SK-OV-3)
Sex of cell Female
Age at sampling 64Y
Category Cancer cell line
Publications

PubMed=2565764
Bradley G., Naik M., Ling V.
P-glycoprotein expression in multidrug-resistant human ovarian carcinoma cell lines.
Cancer Res. 49:2790-2796(1989)

PubMed=17726699; DOI=10.1002/gcc.20492
Buys T.P.H., Chari R., Lee E.H.L., Zhang M., MacAulay C., Lam S., Lam W.L., Ling V.
Genetic changes in the evolution of multidrug resistance for cultured human ovarian cancer cells.
Genes Chromosomes Cancer 46:1069-1079(2007)

Cross-references
Gene expression databases GEO; GSM183342
GEO; GSM183344
Other Wikidata; Q54954807