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Cellosaurus BT 145 (CVCL_IP10)

Cell line name BT 145
Synonyms BT-145; BT145
Accession CVCL_IP10
Resource Identification Initiative To cite this cell line use: BT 145 (RRID:CVCL_IP10)
Comments Characteristics: Low-passage-number culture.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=27723727).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=25184684; DOI=10.1371/journal.pone.0106694
Holmberg Olausson K., Maire C.L., Haidar S., Ling J., Learner E., Nister M., Ligon K.L.
Prominin-1 (CD133) defines both stem and non-stem cell populations in CNS development and gliomas.
PLoS ONE 9:E106694-E106694(2014)

PubMed=25366336; DOI=10.1093/neuonc/nou303
Green A.L., Ramkissoon S.H., McCauley D., Jones K., Perry J.A., Hsu J.H.-R., Ramkissoon L.A., Maire C.L., Hubbell-Engler B., Knoff D.S., Shacham S., Ligon K.L., Kung A.L.-J.
Preclinical antitumor efficacy of selective exportin 1 inhibitors in glioblastoma.
Neuro-oncol. 17:697-707(2015)

PubMed=27723727; DOI=10.1038/nbt.3697
Stevens M.M., Maire C.L., Chou N., Murakami M.A., Knoff D.S., Kikuchi Y., Kimmerling R.J., Liu H.-Y., Haidar S., Calistri N.L., Cermak N., Olcum S., Cordero N.A., Idbaih A., Wen P.Y., Weinstock D.M., Ligon K.L., Manalis S.R.
Drug sensitivity of single cancer cells is predicted by changes in mass accumulation rate.
Nat. Biotechnol. 34:1161-1167(2016)

Cross-references
Anatomy/cell type resources BTO; BTO:0005950
Chemistry resources PharmacoDB; BT145_116_2019
Encyclopedic resources Wikidata; Q54798421
Entry history
Entry creation03-Mar-2017
Last entry update29-Jun-2023
Version number8