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Cellosaurus KBM-3/AMSA (CVCL_IP19)

[Text version]

Cell line name KBM-3/AMSA
Accession CVCL_IP19
Resource Identification Initiative To cite this cell line use: KBM-3/AMSA (RRID:CVCL_IP19)
Comments Selected for resistance to: ChEBI; CHEBI:2687; Amsacrine.
Derived from sampling site: Peripheral blood.
Sequence variations TOP2A p.Arg487Lys (c.1460G>A) (PubMed=1311390).
Disease Acute myelomonocytic leukemia (NCIt: C7463)
Acute myelomonocytic leukemia (ORDO: Orphanet_517)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A425 (KBM-3)
Sex of cell Female
Age at sampling 32Y
Category Cancer cell line
Publications

PubMed=1311390; DOI=10.1016/0022-2836(92)90245-F
Lee M.-S., Wang J.C., Beran M.
Two independent amsacrine-resistant human myeloid leukemia cell lines share an identical point mutation in the 170 kDa form of human topoisomerase II.
J. Mol. Biol. 223:837-843(1992)

Cross-references
Other Wikidata; Q54899583
Entry history
Entry creation03-Mar-2017
Last entry update12-Mar-2020
Version number6