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Cellosaurus TOV-112DR (CVCL_IQ56)

[Text version]
Cell line name TOV-112DR
Synonyms TOV112DR
Accession CVCL_IQ56
Resource Identification Initiative To cite this cell line use: TOV-112DR (RRID:CVCL_IQ56)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:31355; Carboplatin (CBP; Paraplatin).
Omics: Deep proteome analysis.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; 2514; CTNNB1; Simple; p.Ser37Ala (c.109T>G); ClinVar=VCV000376235; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11100; SMARCA4; Simple; p.Leu639fs (c.1915delC); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Unspecified (from parent cell line).
Disease Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Endometrioid carcinoma of ovary (ORDO: Orphanet_454723)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3612 (TOV-112D)
Sex of cell Female
Age at sampling 42Y
Category Cancer cell line
Publications

PubMed=27561551; DOI=10.1038/ncomms12645
Coscia F., Watters K.M., Curtis M., Eckert M.A., Chiang C.Y., Tyanova S., Montag A., Lastra R.R., Lengyel E., Mann M.
Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status.
Nat. Commun. 7:12645.1-12645.14(2016)

Cross-references
Cell line databases/resources cancercelllines; CVCL_IQ56
Encyclopedic resources Wikidata; Q54972796
Proteomic databases PRIDE; PXD003668
Entry history
Entry creation03-Mar-2017
Last entry update05-Oct-2023
Version number10