ID   CAP
AC   CVCL_IQ88
SY   CEVEC's Amniocyte Production; N52.E6
DR   Lonza; 1310
DR   Wikidata; Q54907345
RX   Patent=US6558948;
RX   PubMed=11044912;
RX   PubMed=22373410;
RX   PubMed=22373426;
RX   PubMed=22821436;
WW   https://cevec.com/technology/
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSMZ); ACC-2416.
CC   Characteristics: Used for stable production of recombinant proteins.
CC   Transfected with: UniProtKB; P03281; Adenovirus 5 pIX.
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5 [Note=E1A/E1B].
CC   Derived from site: In situ; Amniotic fluid; UBERON=UBERON_0000173.
CC   Cell type: Amniocyte; CL=CL_0002323.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_IQ89 ! N52.F4
AG   Fetus
CA   Transformed cell line
DT   Created: 03-03-17; Last updated: 05-10-23; Version: 9
//
RX   Patent=US6558948;
RA   Kochanek S., Schiedner G.;
RT   "Permanent amniocytic cell line, its production and use for the
RT   production of gene transfer vectors.";
RL   Patent number US6558948, 06-May-2003.
//
RX   PubMed=11044912; DOI=10.1089/104303400750001417;
RA   Schiedner G., Hertel S., Kochanek S.;
RT   "Efficient transformation of primary human amniocytes by E1 functions
RT   of Ad5: generation of new cell lines for adenoviral vector
RT   production.";
RL   Hum. Gene Ther. 11:2105-2116(2000).
//
RX   PubMed=22373410; DOI=10.1186/1753-6561-5-S8-P66;
RA   Essers R., Kewes H., Schiedner G.;
RT   "Improving volumetric productivity of a stable human CAP cell line by
RT   bioprocess optimization.";
RL   BMC Proc. 5 Suppl. 8:P66-P66(2011).
//
RX   PubMed=22373426; DOI=10.1186/1753-6561-5-S8-P133;
RA   Wolfel J., Essers R., Bialek C., Hertel S., Scholz-Neumann N.,
RA   Schiedner G.;
RT   "CAP-T cell expression system: a novel rapid and versatile human cell
RT   expression system for fast and high yield transient protein
RT   expression.";
RL   BMC Proc. 5 Suppl. 8:P133-P133(2011).
//
RX   PubMed=22821436; DOI=10.1007/s00253-012-4238-2;
RA   Genzel Y., Behrendt I., Rodig J., Rapp E., Kueppers C., Kochanek S.,
RA   Schiedner G., Reichl U.;
RT   "CAP, a new human suspension cell line for influenza virus
RT   production.";
RL   Appl. Microbiol. Biotechnol. 97:111-122(2013).
//