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Cellosaurus Bo-786-O (CVCL_IS21)

[Text version]

Cell line name Bo-786-O
Accession CVCL_IS21
Resource Identification Initiative To cite this cell line use: Bo-786-O (RRID:CVCL_IS21)
Comments Transfected with: UniProtKB; P08659; Firefly luciferase.
Transfected with: UniProtKB; P42212; GFP.
Sequence variations Homozygous for PTEN p.Gln149Ter (c.445C>T) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
Heterozygous for TP53 c.560-2A>G; splice acceptor mutation and p.Pro278Ala (c.832C>G) (ClinVar=VCV000376645) (from parent cell line).
Homozygous for VHL p.Gly104fs*55 (c.311delG) (from parent cell line).
Disease Renal cell carcinoma (NCIt: C9385)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1051 (786-O)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line

PubMed=24587095; DOI=10.1371/journal.pone.0089880
Satcher R.L., Pan T., Cheng C.J., Lee Y.-C., Lin S.-C., Yu G., Li X., Hoang A.G., Tamboli P., Jonasch E., Gallick G.E., Lin S.-H.
Cadherin-11 in renal cell carcinoma bone metastasis.
PLoS ONE 9:E89880-E89880(2014)

PubMed=27993170; DOI=10.1186/s12943-016-0565-8
Brodaczewska K.K., Szczylik C., Fiedorowicz M., Porta C., Czarnecka A.M.
Choosing the right cell line for renal cell cancer research.
Mol. Cancer 15:83-83(2016)

Other Wikidata; Q54797688
Entry history
Entry creation03-Mar-2017
Last entry update02-Jul-2020
Version number7